Hypersil ODS HPLC Column - Thermo Scientific Original Octadecylsilane Phase

The Thermo Scientific Hypersil ODS is one of the original and most established reversed-phase HPLC columns available. Based on the legendary Hypersil spherical silica, the ODS (Octadecylsilane) bonded phase has been a standard reference column in analytical chemistry laboratories worldwide.

Key Specifications:

• Brand: Thermo Fisher Scientific
• Phase: ODS (C18, Octadecylsilane)
• Particle Size: 5.0 µm
• Pore Size: 120 Å
• Mode: Reversed Phase
• USP Classification: L1
• Inner Diameter: 4.6 mm
• Length: 250 mm

Why Choose Hypersil ODS?

The Hypersil ODS column is built on Hypersil's proprietary spherical silica, which provides uniform particle shape and size distribution. This results in high column efficiency, low back pressure, and predictable retention behavior across different batches.

Unlike newer BDS columns, the Hypersil ODS uses a traditional bonding process that provides slightly different selectivity — making it valuable when your established method specifically calls for an ODS-type phase.

Applications:

• Pharmacopeia methods requiring USP L1 ODS phases
• Environmental analysis (EPA methods for organic pollutants)
• Industrial quality control
• Legacy method support where ODS selectivity is specified
• Teaching and research laboratories

Hypersil ODS vs. Hypersil BDS — What Is the Difference?

The Hypersil ODS uses traditional silica without base deactivation, providing classic ODS selectivity. The Hypersil BDS adds base-deactivated silica to reduce silanol activity for improved basic compound analysis. Choose ODS when your method specification requires it; choose BDS for new method development with basic analytes.

Available at Eke Lab Shop with worldwide shipping. Contact us for pricing and technical support.